PLANTS USED BY THE INDIGENOUS PEOPLE OF ODEDA, OGUN STATE, NIGERIA FOR DIFFERENT AILMENTS: ETHNOBOTANICAL REPORTS AND PHARMACOLOGICAL EVIDENCE

Authors

  • D. B. OLUNLADE
  • R. A. AJIBADE
  • K. O. ADELEKE
  • T. SALIHU
  • O. A. ADEKOYA
  • O. T. ADENUBI

Keywords:

medicinal plants, ailment, ethnomedicine, questionnaire, knowledge, Odeda

Abstract

The indigenous people of rural and semi-urban regions of Nigeria have a rich traditional medicine practice (TMP) heritage. Despite their wealth of knowledge on the use of plants as medicines, many of these plants have not been adequately explored. This study aimed at documenting, reviewing and validating plant species and their therapeutic benefits by the indigenous people of Ọdédá Local Government Area (LGA), Ogun State. Semi-structured questionnaire was used to gather information on socio-demographic data and ethno-medicinal plants/practices from 21 traditional medicine practitioners in ten villages across the LGA. Information collected included the plant species/parts used, ailments, common/vernacular names of the plants and methods of preparation/administration. An extensive literature survey was thereafter done to authenticate the veracity of the claims and find extra information on what is known about the named plants. Diseases frequently managed in this study area were fever/malaria, typhoid and arthritis. A total of 36 plant species belonging to 27 plant families were documented with their leaves mostly used plant part as oral decoctions. Aframomum melegueta and Citrus aurantifolia were the plant species with the highest relative frequency of citation. Approximately 83 % of the named plant species were found to have similar ethnomedicinal uses with studies conducted in other parts of the world and 99 % have been reported to be pharmacologically active in the literature. Lack of proper documentation can lead to loss of the traditional knowledge which threatens the sustenance of rural healthcare system. Standardization, development of an integrative curriculum and formal training in TMP in Nigeria is urgently needed.

 

 

References

Abdulsalami, H., Mudi, S.Y. Daudu, O.A.Y., Aliyu, B.S., Adabara, N.S., Hamza, R.U. 2020. Ethnobotanical survey of medicinal plants used in the treatment of gastrointestinal tract infections in Ebira land, Kogi state, Nigeria. Journal of Medicinal Plants Studies 8(1): 38-44.

Adenubi, O.T., Olunlade, D.B., Ajibade, R.A., Adeleke, K.O. 2019. Ethnoveterinary medicine of the indigenous people of Odeda local government area, Ogun State, Southwest Nigeria. International Journal of Agricultural Research and Development 15(1): 70-98.

Afolabi, O.J., Abejide, A.E. 2020. Antiplasmodial activities of Morinda lucida (Benth) and Alstonia boonei (De wild) in mice infected with Plasmodium berghei. Bulletin of the National Research Centre 44: 85. https://doi.org/10.1186/s42269-020-00342-8

Agbodeka, K., Gbekley, H.E., Karou, S.D., Anani, K., Agbonon, A., Tchacondo, T., Batawila, K., Simpore, J., Gbeassor, M. 2016. Ethnobotanical study of medicinal plants used for the treatment of malaria in the Plateau Region, Togo. Pharmagcognosy Research 8(1): S12-S18.

Alalwan, T.A., Alkhuzai, J.A., Jameel, Z., Mandeel, Q.A.M. 2019. Quantitative ethnobotanical study of some medicinal plants used by herbalists in Bahrain. Journal of Herbal Medicine 17: 100278. https://doi.org/10.1016/j.hermed.2019.100278

Amitani, M., Cheng, K., Asakawa, A., Amitani, H., Kairupan, T.S., Sameshima, N., Shimizu, T., Hashiguchi, T., Inui, A. 2015. Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors. Peer Journals 3: e1105 https://doi.org/10.7717/peerj.1105

Amori, A.A., Oduntan, O.O., Okeyode, I.C., Ojo, S.O. 2013. Heavy metal concentration of groundwater deposits in Odeda region, Ogun state, Nigeria. E3 Journal of Environmental Research and Management 4: 253-259.

Aschale, Y., Mengist, A., Bitew, A., Kassie, B., Talie, A. 2018. Prevalence of malaria and associated risk factors among asymptomatic migrant laborers in West Armachiho District, Northwest Ethiopia. Research and Reports in Tropical Medicine 9: 95-101.

Asuzu, C.C., Akin-Odanye E.O, Asuzu, M.C., Holland, J. 2019. A socio-cultural study of traditional healers role in African health care. Infectious Agents and Cancer 14: 15. doi: 10.1186/s13027-019-0232-y

Aziz, M.A., Adnan, M., Khan, A.H., Shahat, A.A., Al-Said, M.S., Ullah, R. 2018. Traditional uses of medicinal plants practiced by the indigenous communities at Mohmand Agency, FATA, Pakistan. Journal of Ethnobiology and Ethnomedicine 14(1): 2. doi: 10.1186/s13002-017-0204-5

Azmir, J., Zaidul, I.S.M., Rahman, M.M., Sharif, K. M., Mohamed, A., Sahena, F., Jarulul, M.H.A., Ghafoor, K., Norulaini, N.A.N., Omar, A.K.M. 2013. Techniques for extraction of bioactive compounds from plant materials: A review. Journal of Food Engineering 117(4): 426-436.

Batiha, G.E., Alkazmi, L.M., Nadwa, E.H., Rashwan, E.K., Beshbishy, A.M. Shaheen, H., Wasef, L. 2020. Physostigmine: A plant alkaloid isolated from Physostigma venenosum: A review on pharmacokinetics, pharmacological and toxicological activities. Journal of Drug Delivery and Therapeutics 10: 187-190.

Bernardini, S., Tiezzi, A., Laghezza Masci, V., Ovidi, E. 2018. Natural products for human health: an historical overview of the drug discovery approaches. Natural Product Research 32(16): 1926-1950.

Chen, S., Yu, H., Luo, H., Wu, Q., Li, C., Steinmetz, A. 2016. Conservation and sustainable use of medicinal plants: problems, progress, and prospects. Chinese Medicine 11: 37. DOI 10.1186/s13020-016-0108-7

Chithambo, B., Noundou, X.S., Krause, R.W.M. 2017. Anti-malarial synergy of secondary metabolites from Morinda lucida Benth. Journal of Ethnopharmacology 199: 91-96.

Crofford, J.L. 2013. Use of NSAIDs in treating patients with arthritis. Arthritis Research and Therapy 15: S2.

Ediriweera, M.K., Tennekoon, K.H., Samarakoo, S.R. 2017. A review on ethnopharmacological applications, pharmacological activities, and bioactive compounds of Mangifera indica (Mango). Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2017/6949835

Elujoba, A.A., Fell, A.F., Linley, P.A., Maitland, D.J. 1990. Triterpenoid saponins from fruit of Lagenaria breviflora. Phytochemistry 29(10): 3281-3285.

Ettebong, E., Ubulom, P., Etuk, A. 2019. Antiplasmodial activity of methanol leaf extract of Citrus aurantifolia (Christm) Swingle. Journal of Herbmed Pharmacology 8(4): 274-280.

Gakuya, D.W, Itonga, S.M, Mbaria, J.M., Muthee, J.K., Musau, J.K. 2013. Ethnobotanical survey of biopesticides and other medicinal plants traditionally used in Meru central district of Kenya. Journal of Ethnopharmacology 145: 547-553.

Ganesh, D., Fuehrer, H. 2012. Antiplasmodial activity of flavonol quercetin and its analogues in Plasmodium falciparum: evidence from clinical isolates in Bangladesh and standardized parasite clones. Parasitology Research 110: 2289-2295.

Garbi, M., Osman, E.E., Kabbashi, A. 2015a. Anticancer activity of Bauhinia rufescens (Lam) leaf extracts on MCF-7 human breast cancer cells. Journal of Medicinal Plants Studies 3(5): 103-106.

Inbaneson, S. J., Sundaram,R. Palavesam S. 2012. In vitro antiplasmodial effect of ethanolic extracts of traditional medicinal plant Ocimum species against Plasmodium falciparum, Asian Pacific Journal of Tropical Medicine 5(2): 103-106.

Isola, O.I. 2013. The" relevance" of the African traditional medicine (alternative medicine) to health care delivery system in Nigeria. The Journal of Developing Areas 319-338.

Jima, T.T., Megersa, M. 2018. Ethnobotanical study of medicinal plants used to treat human diseases in Berbere District, Bale Zone of Oromia Regional State, South East Ethiopia. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2018/8602945

Kamatenesi, M.M., Acipa, A., Oryem-Origa, H. 2011. Medicinal plants of Otwal and Ngai Sub Counties in Oyam District, Northern Uganda. Journal of Ethnobiology 7(7): 1-14.

Kankara, S.S., Ibrahim, M.H., Mustafa, M., Go, R., 2015. Ethnobotanical survey of medicinal plants used for traditional maternal healthcare in Katsina state, Nigeria. South African Journal of Botany 97: 165-175.

Kemboi, D., Peter, X., Langat, M., Tembu, J. 2020. A review of the ethnomedicinal uses, biological activities, and triterpenoids of Euphorbia species. Molecules 25: 4019. doi:10.3390/molecules25174019

Kola, P., Metowogo, K., Kantati, P., Lawson-Evi, P., Kpemissi, M., El-Hallouty, S.M., Mouzou, A.P., Eklu-Gadegbeku, K., Aklikokou, K.A. 2020. Ethnopharmacological survey on medicinal plants used by traditional healers in Central and Kara Regions of Togo for antitumor and chronic wound healing effects. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2020/6940132

Mabaleha, M.B., Zietsman, P.C., Wilhelm, A., Bonnet, S.L. 2019. Ethnobotanical survey of medicinal plants used to treat mental illnesses in the Berea, Leribe, and Maseru Districts of Lesotho. Natural Product Communications 14(7). DOI: 10.1177/1934578X19864215

Moshi, J.M., Otieno, D.F., Weisheit, A. 2012. Ethnomedicine of the Kagera Region, North western Tanzania. Part 3: plants used in traditional medicine in Kikuku village, Muleba District. Journal of Ethnobiology and Ethnomedicine 8,14. https://doi.org/10.1186/1746-4269-8-14

Muhammad, A., Sirat, H.M. 2013. COX-2 inhibitors from stem bark of Bauhinia rufescens Lam. (Fabaceae). EXCLI Journal 12: 824-830.

Nabatanzi A., Nkadimeng S.M., Lall N., Kabasa J.D., McGaw, J.L. 2020. Ethnobotany, phytochemistry and pharmacological activity of Kigelia africana (Lam.) Benth. (Bignoniaceae). Plants (Basel) 9(6): 753. doi:10.3390/plants9060753

National Biodiversity Report 2015. Federal Republic of Nigeria. Natural products. Molecules 21: 559. doi:10.3390/molecules21050559

Nouri, F., Nourollahi-Fard, S.R., Foroodi, H.R., Sharifi, H. 2016. In vitro anthelmintic effect of Tobacco (Nicotiana tabacum) extract on parasitic nematode, Marshallagia marshalli. Journal of Parasitic Diseases 40(3), 643-647.

Olasehinde, G.I., Ojurongbe, D.O., Akinjogunla, O.J., Egwari, L.O., Adeyeba, A.O. 2015. Prevalence of malaria and predisposing factors to antimalarial drug resistance in southwestern Nigeria. Research Journal of Parasitology 10(3): 92-101.

Oran, S.A.S., Al-Eisawi, D.M.H. 2015. Ethnobotanical survey of the medicinal plants in the central mountains (North-South) in Jordan. Journal of Biodiversity and Environmental Sciences 6(3): 381-400.

Salihu, T, Olukunle, J.O., Adenubi, O.T., Mbaoji, C., Zarma, M.H. 2018. Ethnomedicinal plant species commonly used to manage arthritis in North-West Nigeria. South African Journal of Botany 118: 33-43.

Salihu, T., Adenubi, O.T., Mbaoji, C.O., Ojogbo, I.A., Abdullahi, A. 2020. A review of ethnoveterinary botanicals used for tick control in Wukari, Taraba State, North Eastern Nigeria. Egyptian Journal of Veterinary Sciences 51(3): 421-437.

Schultz, F., Anywar, G., Wack, B., Quave, C.L., Garbe, L.A. 2020. Ethnobotanical study of selected medicinal plants traditionally used in the rural Greater Mpigi region of Uganda. Journal of Ethnopharmacology 256: 112742. https://doi.org/10.1016/j.jep.2020.112742

Schumacher, M., Cerella, C., Reuter, S., Dicato, M., Diederich, M., 2011. Anti-inflammatory, pro-apoptotic, and anti-proliferative effects of a methanolic neem (Azadirachta indica) leaf extract are mediated via modulation of the nuclear factor-κB pathway. Genes and Nutrition 6(2): 149-160.

Sen, S., Chakraborty, R. 2017. Revival, modernization and integration of Indian traditional herbal medicine in clinical practice: Importance, challenges and future. Journal of Traditional and Complementary Medicine 7(2): 234-244.

Soaga, J.A., Adekunle, E.O. 2015. Public awareness and willingness to pay for environmental services of forest trees in Odeda LGA, Ogun State, Nigeria. XIV World Forestry Congress, Durban, South Africa 1-9.

Tardío, J., Pardo-de-Santayana M. 2008. Cultural importance indices: A comparative analysis based on the useful wild plants of Southern Cantabria (Northern Spain) 1. Economic Botany 62: 24-39.

Tesfaye, S., Belete, A., Engidawork, E., Gedif, T., Asre, K. 2020. Ethnobotanical study of medicinal plants used by traditional healers to treat cancer-like symptoms in Eleven Districts, Ethiopia. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2020/7683450

Umair, M., Altaf, M., Abbas, A.M. 2017. An ethnobotanical survey of indigenous medicinal plants in Hafizabad district, Punjab, Pakistan. PLoS ONE 12(6): e0177912. https://doi.org/10.1371/journal.pone.0177912

Wanjohi, B.K., Sudoi, V., Njenga, E.W., Kipkore, W.K. 2020. An ethnobotanical study of traditional knowledge and uses of medicinal wild plants among the Marakwet Community in Kenya. Evidence-Based Complementary and Alternative Medicine. https://doi.org/10.1155/2020/3208634

Weber, S.S., Kaminski, K.P., Perret, J., Leroy, P., Mazurov, A., Peitsch, M.C., Ivanov, N.V., Hoeng, J. 2019. Antiparasitic properties of leaf extracts derived from selected Nicotiana species and Nicotiana tabacum varieties. Food and Chemical Toxicology 132: 110660. https://doi.org/10.1016/j.fct.2019.110660

Yuan, H., Ma, Q., Ye, L., Piao, G. 2016. The traditional medicine and modern medicine from natural products. Molecules 21(5): 559.

Zizka, A., Thiombiano, A., Dressler, S., Nacoulma, B.M.I., Ouédrao, A., Ouédraogo, I., Ouédraogo, O., Zizka, G., Hahn, K., Schmidt, M. 2015. Traditional plant use in Burkina Faso (West Africa): a national-scale analysis with focus on traditional medicine. Journal of Ethnobiology and Ethnomedicine 11: 9. doi:10.1186/1746-4269-11-9

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2022-11-18

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