ETHNOBOTANICAL SURVEY AND PHYTOCHEMICAL ANALYSIS OF MEDICINAL PLANTS USED IN SOUTHWESTERN PART OF NIGERIA AS ANALGESICS
Keywords:
Ethnobotanical, Herbal remedy, pain management, southwestern NigeriaAbstract
The gradual threat to plants and the inevitable disappearance of the aged Traditional Medical Practitioner are posing an impending time limit for people to learn, acquire, and document the rich medical cultural endowment. This cultural endowment is essential for the benefit of all Africans and indeed the entire mankind. Hence, the urgent need for continual ethno-botanical survey of medicinal plants in Nigeria. Ethnobotanical survey was carried out using structured questionnaire to obtain information from trado-medical practitioners from Ogun, Oyo, Ondo and Lagos States. Samples of eleven commonly used plants were collected and authenticated at the Forest Herbarium Ibadan, where voucher specimens were deposited. Extracts of each plant (leaf, root or seeds) were obtained by soxhlet extraction using methanol, diethyl ether and water, concentrated and screened for phytochemical constituents using standard procedures. Thirty-one plant species belonging to 24 families are being used as analgesics, of which Macrosphyra longistyla, Strophanthus hispidus, Buchholzia coriacea, Calliandra portoricensis, Secamone afzeli, Chasmanthera dependens, Spilanthes filicaulis, Moringa oleifera, Clerodendrum volubile, Petiveria alliacea, Carpolobia lutea were prevalent. Methanol and diethyl ether extracts of the plants contained alkaloids, saponins, tannins, phenols, anthraquinones and glycosides while, aqueous extracts contained alkaloids, saponins and glycoside
References
Adegoke, B.O., Odole, A.C., Adeyinka, A.A. 2018. Adolescent low back pain among secondary school students in Ibadan, Nigeria. African Health Sciences 15(2): 429-437.
Akinyemi, O., Oyewole, S.O., Jimoh, K.A. 2018. Medicinal plants and sustainable human health: a review. Horticulticulture International Journal 2(4): 194-195.
Akodu, A. K., Ashalejo, Z.O. 2019. Work-related musculoskeletal disorders and work ability among hospital nurses Journal of Taibah University Medical Sciences 14(3): 252–261.
Ayanniyi, O., Nudamajo, O.S., Mbada, C.E. 2016. Pattern of work-related musculoskeletal disorders among Nigerian Hospital workers. Journal of Environmental and Occupational Science 5(1): 18-24.
Barkin, R.L. 2008. Extended-release Tramadol (ULTRAM ER): a pharmacotherapeutic, pharmacokinetic, and pharmacodynamic focus on effectiveness and safety in patients with chronic/persistent pain. American Journal of Therapeutic 15(2): 157-166.
Brunner, J.H. 1984. Direct Spectrophotometer determination of Saponin. Analytical Chemistry 34: 1314 - 1326.
Calixto, J.B., Bemith, A., Ferreira, J., Santos, A.R., Cechinel, F.V., Yunes, R.A. 2000. Natural occurring antinociceptive substances from plant. Phytotheraphy Research 14: 401-418.
Chindo, B., Anuka, J., Isaac, E., Ahmadu, A., Tarfa, F., Gamaniel, K. 2010. Saponins are involved in anti-inflammatory and analgesic properties of Ficus platyphylla stem bark. International Journal of Biological and Chemical Sciences 4(2): 415-423.
Cragg, G.M., Newman, D.J. 2001. Medicinals for the Millennia. Annals of the New York Academy of Sciences 953: 3-25.
Ebomoyi, E.W. 2009. Genomics in traditional African healing and strategies to integrate Traditional Healers into Western-Type Health Care Services. A Retrospective Study Researcher 1(6): 69-79.
Erukainure, O.L., Oke, O.V., Ajiboye, A. J., Okafor, O.Y. 2011. Nutritional qualities and phytochemical constituents of Clerodendrum volubile, a tropical non-conventional vegetable. International Food Research Journal 18(4): 1393–1399.
Evans, P.K.A., Mohammed, I., Halimatu-Sadia, I., Rabiatu, H.H., Stephen, Y.G. 2018: "Concurrent Use of Herbal and Orthodox Medicines among Residents of Tamale, Northern Ghana, Who Patronize Hospitals and Herbal Clinics", Evidence-Based Complementary and Alternative Medicine, vol. 2018, Article ID 1289125, 8 pages, 2018. https://doi.org/10.1155/2018/1289125.
Fakeye, O.T., Adisa, R., Musa, E.I. 2009. Attitude and use of herbal medicines among pregnant women in Nigeria. BMC Complementary and Alternative Medicine 9:53-59.
Fatima Ez-Zahra Amrati, Mohammed Bourhia, Meryem Slighoua, Ahmad Mohammad Salamatullah, Abdulhakeem Alzahrani, Riaz Ullah, Amina Bari, Dalila Bousta 2021. Traditional medicinal knowledge of plants used for cancer treatment by communities of mountainous areas of Fez-Meknes-Morocco: Saudi Pharmaceutical Journal 29(10): 1185–1204.
Garima, M., Pradeep, S., Ramesh, V., Sunil, K., Saurabh, S.K.K., Khosa, R.L. 2011. Traditional uses, phytochemistry and pharmacological properties of Moringa oleifera plant: An overview. Der Pharmacia Lettre 3(2): 141-164.
Haidan Yuan, Qianqian Ma, Li Ye, Guangchun Piao 2016. The Traditional Medicine and Modern Medicine from Natural Products: Molecule 21 (559); doi:10.3390/molecules21050559.
Harbone, J.B. 1973. Textbook of Phytochemical methods. 1st Edition. Champman and Hall Ltd. London, 279.
Herbert, A.O., Josephat, M.C., Agozie, C.U., Christopher, B.E., Ikenna, K.N. 2012. Acetaminophen use (and/or misuse) in children in Enugu, South East, Nigeria. BioMed Central Pediatrics 12: 103.
Herbert, E.B. 2012. Press coverage of traditional medical practice in Nigeria. Journal of communication 3(2): 75-78.
Kwaghe, A.V., Ambali, A.G. 2009. Preliminary Phytochemical Screening of Fresh and Dried Moringa oleifera Leaves and that of Chloroform, Ethylacetate and n-Butanol Fractions. Sahel Journal of Veterinary Science 8(2): 26-31.
Michael, H. 2003. Ethnobotany and Natural products; The search for New Molecules, New Treatments of old Disease or a Better understanding of Indigenous cultures? Current Topics in Medicinal chemistry 3: 29-42.
Nair, R., Chanda, S. 2007. Antibacterial activities of some medicinal plants of the Western Region of India. Turkish Journal of Biology 31: 231-236.
Ogunwa, T.H., Ajiboye, S.A., Sholanke, D.R., Awe, O.B., Ademoye, T.A., Oloye, O.B., Ilesanmi O.C. 2015. Nutritional Evaluation of Clerodendrum volubile (Marugbo) Leaves. Asian Journal of Plant Science and Research 5(11): 26-31.
Ojiako, E.N. 2014. Phytochemical analysis and antimicrobial screening of Moringa oleifera leaves extract. The International Journal of Engineering and Sciences 3(3): 32-35.
Okwu, D.E., Ndu, C.U. 2006. Evaluation of the Phytonutrients, Mineral and Vitamin Contents of Some Varieties of Yam (Dioscorea sp.) International Journal of Molecular Medicine and Advance Science 2(2): 199-203.
Prashant, T., Bimlesh, K., Mandeep, K., Gurpreet, K., Harleen, K. 2011. Phytochemical Screening and Extraction: A Review. Internationale pharmaceutica scienncia 1(1): 98-106.
Sandul, Y., Paramasivan, R. 2014. Work related musculoskeletal disorders among health care professionals. A cross sectional assessment of risk factors in a tertiary hospital, India. Indian Journal of Occupational and Environmental Medicine 18(2): 75-81.
Saxhaug, K.E., Lundqvist, C. 2014. Medication-overuse headache: a review. Journal of Pain Research 7: 367–378.
Sofowora, A. 1993. Medicinal Plants and Traditional Medicine in Africa 2nd Edition. University Spectrum Books Ltd., Ibadan, Nigeria. pp.289.
Trease, G.E., Evans, W.C. 1989. A Textbook of Pharmacognosy (14th Ed.). Bailliere Tinall Ltd, London. pp.579.
Tsang, A., Von Korff, M., Lee, S., Alonso, J., Karam, E., Angermeyer, M.C., Borges, G.L., Bromet, E.J., de Girolamo, G., de Graaf, R., Gureje, O., Lepine, J.P., Haro, J.M., Levinson, D., Oakley, B.M.A., Posada-Villa, J., Seedat, S., Watanabe, M. 2008. Common chronic pain conditions in developed and developing countries: gender and age differences and comorbidity with depression-anxiety disorders. The Journal of Pain 9: 883–891.
Uche, F.I., Aprioku, J.S. 2008. The Phytochemical Constituents, Analgesic, and Anti-inflammatory effects of methanol extract of Jatropha curcas leaves in Mice and Wister albino rats. Journal of Applied Science and Environmental Management 12(4): 99 – 102.
Vaghasiya, Y. 2009. Screening of some medicinal plants for antimicrobial properties-phytochemical and pharmacological studies of a selected medicinal plant. Unpublished Ph.D. thesis, pp.1-18.
Zwawua, O., Ismail, R., Mohd Yasin Mohd Azhar, M.M., Noor, N.M., Iorvaa, T. 2020. Development, Validity and Reliability of Tramadol Use and Misuse Knowledge Assessment Questionnaire. African Journal of Drug and Alcohol Studies 19(1): 11-24
