ESTIMATION OF OPTIMAL DOSE OF BOVINE SOMATOTROPIN FOR MAXIMUM MILK YIELD RESPONSE IN WEST AFRICAN DWARF GOATS
DOI:
https://doi.org/10.51406/jagse.v10i2.1089Keywords:
WAD goats, milk yield, bovine somatotropin.Abstract
Optimal dose of bovine somatotropin (bST) in a sustained-delivery vehicle required for maximum milkyield response was estimated in twenty-four lactating West African Dwarf (WAD) goats in three 14-dayperiods using quadratic equation. The goats were divided equally into four treatment groups, eachcomprising six does. The first group (control, T0) received no bST while the other groups received bST(T1, 20 mg; T2, 40 mg; T3, 60 mg) injected at 2-week intervals commencing from the 7th week postpartumfor 6 weeks. Does were milked twice daily (7:30 am and 7:30 pm) and milk yield recorded daily.Daily milk yield response (DMY) to bST was significantly (p<0.001) influenced by bST dose, day frombST treatment and parity during the 2nd period of bST treatment but only bST dose and parity significantlyinfluenced (p<0.001) DMY during the 1st and 3rd periods of bST treatment. The mean relativeresponse of DMY of bST-treated goats exceeded the control by 48 – 78 % in the entire periods of bSTadministration. Highest predicted response of 80.5 % in the 3rd period and lowest response of 66.2 %in the 1st period of bST treatment (when compared to the control) were observed, thus indicating thatbST positively affected the shape of the lactation curve for possible higher yield in extended lactation.Although, the trend of observed and predicted optimal doses of bST needed for maximum DMY werewell-fitted by the Quadratic equation during the three periods of bST treatment, it varied inconsistentlywith periods of bST treatment (stages of lactation). Therefore, the uniform optimal dose of 50.71 mgper 2 weeks estimated by quadratic equations; Y = 141.318 + 4.097X – 0.041X2, R2 = 99.90), Y =100.912 + 2.926X – 0.030X2, R2 = 99.49 and Y = 5935.420 + 172.071X – 1.735X2, R2 = 99.49 andneeded for maximum DMY of 242.86 ml, relative DMY of 74 % and cumulative milk yield response of10214.29 ml respectively over the entire periods could be adopted in West African Dwarf goats in orderto reduce the complexity of differential injections administered with respect to stages of lactation.References
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F., Pinotti, L., Baraldi-Scesi, L.,
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Dwarf and Red Sokoto goats intensively
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goats during pregnancy and lactation and
their relationship with partial daily milk
yield. M. Agric. Dissertation. Department of
Animal Production and Health, University
of Agriculture, Abeokuta, Nigeria. P. 102.
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on milk yield and mammary gland
histology in West African Dwarf goats. Ph.D
Thesis. Department of Animal Physiology,
University of Agriculture, Abeokuta, Nigeria.
P. 136.
Jammes, H., Dissenhaus, C., Ouriet, V.,
Kayser, C., Postel-Vinay, M.C., Djiane, J.
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the goat: characterization, evolution under
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13: 477-489.
McGuffey, R.K., Basson, R.P., Snyder,
D.L., Block, E., Harrison, J.H., Rakes,
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of somidobove sustained-release administration
on the lactation performance of
dairy cows. J. Dairy Sci., 74: 1263.
Sallam, S.M.A., Nasser, M.E.A., Yousef,
M.I. 2005. Effect of recombinant bovine
somatotropin administration on milk production,
composition and some haematobiochemical
parameters of lactating goats.
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M.A., Vicini, J.L., Ballam, J.M., Lormore,
M.J. 2004. Effect of modified dry
period lengths and bovine somatotropin on
yield and composition of milk from dairy
cows. J. Dairy Sci., 87: 3746-3761.
Baldi, A., Modina, S., Chelli, F., Gandolfi,
F., Pinotti, L., Baraldi-Scesi, L.,
Fantuz, F., Dell`Orto, V. 2002. Bovine
somatoptropin administration to dairy goats
in late lactation: Effects on mammary function,
composition and morphology. J. Dairy
Sci., 85: 1093-1102.
Bauman, D.E., McCutcheon, S.N. 1986.
The effects of growth hormone and prolactin
on metabolism. In: Control of digestion and
metabolism of ruminants. Ed. L.P. Milligan,
W.L. Grovum, A. Dobson, Pp. 436-455.
Englewood Cliffs, NJ: Prentice-Hall.
Bauman, D.E., Vernon, R.G. 1993. Effects
of exogenous bovine somatotropin on
lactation. Ann. Review Nutrition, 13: 437-461.
Bemji, M.N., Osinowo, O.A., Ozoje,
M.O., Adebambo, O.A., Aina, A.B.J.
2007. A comparative study on milk yield
and pre-weaning growth of West African
Dwarf and Red Sokoto goats intensively
managed in South-Western Nigeria.
Ghanaian J. Anim. Sci., 2&3(1): 81-88.
Boutinaud, M., Rousseau, C., Keisler,
D.H., James, H. 2003. Growth hormone
and milking frequency act differently on
goat mammary gland in late lactation. J.
Dairy Sci., 86: 509-520.
Chadio, S.E., Zervas, G., Kiriaku, K.,
Goulas, C., Menegatos, J.,2000. Effects
of recombinant bovine somatotropin administration
to lactating goats. Small Rumin.
Res. 35: 263-269.
Chilliard, Y. 1989. Long-term effects of recombinant
bovine somatotropin (rbST) on
dairy cow performances. Ann. Zootech. (Paris)
37: 159.
Chiofalo, V., Baldi, A., Savoini, G., Polidori,
F., Dell`Orto, V., Politis, I. 1999.
Response of dairy ewes in late lactation to
recombinant bovine somatotropin (rbST).
Small Rumin. Res., 34: 119-125.
Davis, J.J., Sahlu, T., Puchala, R., Herselman,
M.J., Fernadez, J.M., McCann,
J.P., Coleman, S.W. 1999. The effect of
bovine somatotropin on production of lactating
Angora does with kids. J. Anim. Sci.,
17: 17-24.
Dijkstra, J., France., Dhanoe, M.S.,
Maas, J.A., Hanigan, M.D., Rook, A.J.,
Beaver, D.E. 1997. A model to describe
growth patterns of the mammary gland during
pregnancy and lactation. J. Dairy Sci.,
80: 2340-2354.
Etherton, T.D., Bauman, D.E. 1998. Biology
of somatotropin in growth and lactation
of domestic animals. Physiol. Rev.,
78: 745-761.
Gallo, L., Bailoni, L., Schiavon, S., Carnier,
P., Ramanzin, M., Andrighetto, I.,
Bittante, G. 1997. Effect of slow-release
somatotropin on the pattern of milk yield
between and within injection intervals. J.
Dairy Sci., 80: 46-51.
Garssen, G.J., Fennema, J., Lambooy, E.,
Verplanke, J.C. 1989. Short-term treatment
of lactating goats with recombinant bovine
somatotropin and challenges with glucagonsand fructose. Effects on production, metabolism
and hormones. Rep. B-366, Inst.
Anim. Prod. Schoonoord, Inst. Voor
Veeteeltkuhdig, Ziest, The Netherlands.
Google Earth, 2006. http://www.google.earth
Hafez, E.S.E., Jainudeen, M.R.,
Rosnina, Y. 2000. Hormones, growth factors,
and reproduction. In: Reproduction in
farm animals. Edited by E.S.E. Hafez and B.
Hafez, Lippincott Williams and Wilkins
Publishers, USA, 7th edition. P. 33-54.
Hartnell, G.F., Franson, S.E, Bauman,
D.E., Head, H.H., Huber, J.T., Lamb,
R.C., Madsen, K.S., Cole, W.J., Hintz,
R.L. 1991. Evaluation of sometribove in a
prolonged-release system in lactating dairy
cows production responses. J. Dairy Sci.,
74: 2645.
James, I.J. 2000. Changes in udder traits of
West African Dwarf, Red Sokoto and Sahel
goats during pregnancy and lactation and
their relationship with partial daily milk
yield. M. Agric. Dissertation. Department of
Animal Production and Health, University
of Agriculture, Abeokuta, Nigeria. P. 102.
James, I.J. 2009. Effects of bovine somatotropin
on milk yield and mammary gland
histology in West African Dwarf goats. Ph.D
Thesis. Department of Animal Physiology,
University of Agriculture, Abeokuta, Nigeria.
P. 136.
Jammes, H., Dissenhaus, C., Ouriet, V.,
Kayser, C., Postel-Vinay, M.C., Djiane, J.
1996. Growth hormone-binding protein in
the goat: characterization, evolution under
receptor levels. Domest. Anim. Endocrinol,
13: 477-489.
McGuffey, R.K., Basson, R.P., Snyder,
D.L., Block, E., Harrison, J.H., Rakes,
A.H., Emery, R.S., Muller, L.D. 1991. Effect
of somidobove sustained-release administration
on the lactation performance of
dairy cows. J. Dairy Sci., 74: 1263.
Sallam, S.M.A., Nasser, M.E.A., Yousef,
M.I. 2005. Effect of recombinant bovine
somatotropin administration on milk production,
composition and some haematobiochemical
parameters of lactating goats.
http://net.shams.edu.eg/esap/12005issue/4.pdf
SYSTAT, 1992. SYSTAT Computer Package,
Version 5.02 SYSTAT, Inc. 1800
Sherman Av., Evanston, IL USA, 6021,
708.864.5670.
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